Shilong Fan Ph.D.

X-ray facility manager

Main Research Fields

My major work is providing the facility and technology support for macromolecular crystallography research. The facility services included providing all kinds of the automatic devices from liquid handing to crystal screening and optimization, also including data collection and structural solving. The technology support included the crystallography consulting and project research for non-crystallography lab.

Selected Publications

2016

•Ruifeng Yao1*, Zhenhua Ming2*, Liming Yan2*, Suhua Li1*, Fei Wang1, Sui Ma1, Caiting Yu1, Mai Yang1, Li Chen1, Linhai Chen3, Yuwen Li1, Chun Yan1, Di Miao1, Zhongyuan Sun1, Jianbin Yan1, Yuna Sun4, Lei Wang5, Jinfang Chu5, Shilong Fan1, Wei He6, Haiteng Deng1, Fajun Nan3, Jiayang Li5, Zihe Rao2,4†, Zhiyong Lou2† & Daoxin Xie1† （2016）Allosteric activation of the non-canonical hormone receptor DWARF14 by strigolactone （Nature Paper #2016-01-01269C）

•De Dong1*, Kuan Ren1*, Xiaolin Qiu1*, Jianlin Zheng1, Minghui Guo1, Xiaoyu Guan1, Hongnan Liu1, Ningning Li2, Bailing Zhang1,Daijun Yang1, Chuang Ma1, Shuo Wang1, Dan Wu1, Yunfeng Ma1, Shilong Fan2, Jiawei Wang2, Ning Gao2 & Zhiwei Huang1 （2016）  The crystal structure of Cpf1 in complex with CRISPR RNA  （Nature doi:10.1038/nature17944 ）

•Cuicui Shen1,*, Delin Zhang1,*, Zeyuan Guan1,*, Yexing Liu2, Zhao Yang1, Yan Yang1, Xiang Wang1, Qiang Wang1,QunXia Zhang1, Shilong Fan2, Tingting Zou1 & Ping Yin1 （2016）Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins（Nature communication 7:11285 | DOI: 10.1038/ncomms11285）

•Peng Xu,1,2,6 Chengmin Li,3,4,6 Zhihong Chen,1,2 Shuanying Jiang,2 Shilong Fan,2 Jiawei Wang,5 Junbiao Dai,2, Ping Zhu,3,4,* and Zhucheng Chen1,2,7,* (2016)  The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism (Molecular Cell 63, 1–11, September 15, 2016 )

•Xian Xia1–3, Xiaoyu Liu1–3, Tong Li2, Xianyang Fang2 & Zhucheng Chen1,2 (2016) Structure of chromatin remodeler Swi2/Snf2 in the resting state ( Nature structural & molecular biology, VOLUME 23 NUMBER 8 AUGUST 2016 )

•Xiang Wang1*, Jing Feng1*, Yuan Xue1*, Zeyuan Guan1, Delin Zhang1, Zhu Liu2, Zhou Gong3, Qiang Wang1, Jinbo Huang1,Chun Tang2,3, Tingting Zou1,4 & Ping Yin1 （2016） Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex （Nature doi:10.1038/nature18298 ）

•Xiaozhe Xiong1, Tatyana Panchenko2,7, Shuang Yang1, Shuai Zhao1, Peiqiang Yan1,3, Wenhao Zhang3,4, Wei Xie3,4, Yuanyuan Li1,4, Yingming Zhao5, C David Allis2 & Haitao Li1,4,6* (2016) Selective recognition of histone crotonylation by double PHD fingers of MOZ and DP F2 (Nature CHEMICAL BIOLOGY, doi: 10.1038/nchembio.2218)

2015

•Dong Deng1,2,3*, Pengcheng Sun1,2,3*, Chuangye Yan1,2,3, Meng Ke1,2,3, Xin Jiang1,2, Lei Xiong3, Wenlin Ren1,2,Kunio Hirata4,5, Masaki Yamamoto4, Shilong Fan2 & Nieng Yan1,2,3 （2015） Molecular basis of ligand recognition and transport by glucose transporters （Nature，15 October 2015, Vol 526）

•Zehan Hu,1* Qiang Zhou,2* Chenlu Zhang,1* Shilong Fan,1, Wei Cheng,3 Yue Zhao,4 Feng Shao,4 Hong-Wei Wang,1 Sen-Fang Sui,2† Jijie Chai1† (2015) Structural and biochemical basis for induced self-propagation of NLRC4 (Science, 8 October 2015 / Page 1 / 10.1126)

•Teng Zuo1,*, Jianfeng Sun2,3,*, Guiqin Wang4,*, Liwei Jiang1, Yanan Zuo1, Danyang Li1, Xuanling Shi1,Xi Liu2,3, Shilong Fan2,3,Huanhuan Ren4, Hongxing Hu4,w, Lina Sun5, Boping Zhou6, Mifang Liang5, Paul Zhou4,Xinquan Wang2,3 & Linqi Zhang1 (2015) Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection (NATURE COMMUNICATIONS | 6:8855 | DOI: 10.1038)

•Ping Luo1,2,5, Xinzhe Yu2,3,5, Weiguang Wang1,2, Shilong Fan2, Xiaochun Li4 & Jiawei Wang1,2 (2015)  Crystal structure of a phosphorylation-coupled vitamin C transporter ( Nature structural & molecular biology, VOLUME 22 NUMBER 3 MARCH 2015)

•Wen Song1,2,5, Jia Wang1,2,5, Zhifu Han1,2,5, Yifan Zhang3, Heqiao Zhang1, Weiguang Wang1, Junbiao Chang4,Bingshu Xia3, Shilong Fan1,2, Dekai Zhang3, Jiawei Wang1, Hong-Wei Wang1,2 & Jijie Chai1,2  (2015)  Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13   ( Nature structural & molecular biology, VOLUME 22 NUMBER 10 OCTOBER 2015)

•Wen Song1, *, Li Liu2, *, Jizong Wang1, Zhen Wu1, Heqiao Zhang1, Jiao Tang1, Guangzhong Lin1, Yichuan Wang2, 3, Xing Wen2, Wenyang Li2, Zhifu Han1, Hongwei Guo2, 3, Jijie Chai （2015） Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth（Cell Research (2015) :1-12）