Contact information

Email:hangshi@tsinghua.edu.cn

SHI HANG Ph.D.

Assistant Professor

Resume

1992-1996Tsinghua University B.S.

1998-2003University of Massachusetts, Amherst Ph.D.

2004-2006National Institute of Health, NIDDK Research Fellow

2006-2017Rockefeller University Research Associate

2017-PresentSchool of Life Sciences, Tsinghua University Assistant Professor

Main Research Fields

Hang Shi’s laboratory combines structural and functional approaches to investigate, from the molecular perspective, the production, metabolism, function and related regulatory mechanisms of intracellular RNA, and develop biological and medical tools. In addition, we also apply multiple structural biology methods to understand the formation and function of cellular organelles (for instance, cillia).

Selected Publications

1.   Hao, Q.*, Shi, H.*, Jianfeng, S., Blobel, G. Beaded String Modules Form Two Rings around the Nuclear Pore Membrane’s Waist. (sumitted)(*co-first author and corresponding author)  

2.   Li, X., Wang, J., Coutavas, E., Shi. H., Hao, Q., and Blobel, G. (2016) Structure of Niemann-Pick disease protein 1. Proc. Natl. Acad. Sci. U. S. A, 113, 8212-8217.

3.   Singh, N., Blobel, G. Shi, H.* (2015) Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport. Proc. Natl. Acad. Sci. U. S. A, 112, 142-147.

4.   Shi, H.*, Singh, N., Esselborn, F. and Blobel, G. (2014) structure of a myosin•adaptor complex and pairing by cargo. Proc. Natl. Acad. Sci. U. S. A,111, 1082-1090.( *corresponding author)