电话：+86-10-62782664
邮箱：lixueming@mail.tsinghua.edu.cn
副教授
学术指导委员会成员
1998-2002北京科技大学材料物理系 学士
2002-2005北京科技大学材料物理与化学系 硕士
2005-2009中国科学院物理研究所 博士
2009-2013加州大学旧金山分校 博士后
2014-2017清华大学生命科学学院 助理教授
2017-2019清华大学生命科学学院 副教授
2019-至今清华大学生命科学学院 副教授（长聘）
主要从事冷冻电子显微学理论和方法研究，着重于开发和利用最新的电子显微学技术，以提高冷冻电子显微学三维重构的分辨率到原子水平；同时致力于将电子显微学应用到结构生物学研究中去，以解决与结构相关的重要生物学问题。
1. Xinyu Zhang#, Tianfang Zhao#, Jian Chen, Yuan Shen, Xueming Li*.(2022) Epicker is an exemplar-based continual learning approach for knowledge accumulation in cryoEM particle picking. Nature Communication, 2022.13(1):2468
2. Xuzhong Yang#, Chao Lin#, Xudong Chen#, Shouqin Li#, Xueming Li, Bailong Xiao.(2022) Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Nature, 604(7905);377-383.
3. Meijing Li#, Jianfei Ma#, Xueming Li*, Sen-Fang Sui*, In situ cryo-ET structure of phycobilisome - photosystem II supercomplex from red alga, ELife, 2021, 10, e69635.
4. Mingxu Hu#, Qi Zhang#, Jing Yang*, Xueming Li*，Unit quaternion description of spatial rotations in 3D electron cryo-microscopy, Journal of Structural Biology, 2020, 212, 107601
5. Zhaofeng Yan, Meng Yin, Jianan Chen, Xueming Li*.(2020) Assembly and Substrate Recognition of Curli Biogenesis System. Nature Communication, 2020, 11(1), 241.
6. Li Wang, Heng Zhou, Mingmin Zhang, Wenhao Liu, Tuan Deng, Qiancheng Zhao, Yiran Li, Jianlin Lei, Xueming Li*, Bailong Xiao*.(2019) Structure and mechanogating of the mammalian tactile channel PIEZO2. Nature, 573:225-229.
7. Zhou H, Luo F, Luo Z, Li D, Liu C, Li X*.(2019) Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.Anal Chem.,91(17):10996-11003.
8. Li M, Xia X, Tian Y, Jia Q, Liu X, Lu Y, Li M, Li X*, Chen Z*.(2019)Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567(7748):409-413.
9. Zhou H, Luo Z, Li X*.(2019)Using focus ion beam to prepare crystal lamella for electron diffraction.J Struct Biol., 205(3):59-64.
10. Zhao Q, Zhou H, Chi S, Wang Y, Wang J, Geng J, Wu K, Liu W, Zhang T, Dong MQ, Wang J, Li X*, Xiao B*. (2018) Structure and mechanogating mechanism of the Piezo1 channel. Nature, 554(7693):487-492.
11. Mingxu Hu, Hongkun Yu, Kai Gu, Zhao Wang, Huabin Ruan, Kunpeng Wang, Siyuan Ren, Bing Li, Lin Gan, Shizhen Xu, Guangwen Yang*, Yuan Shen*, Xueming Li*, A particle-filter framework for robust cryoEM 3D reconstruction, Nature Methods, 2018, 15, 1083-1089
