Contact information

Xiangle Ren Ph.D.

2011 National Scholarship
2012 National Scholarship Principal Scholarship/Top Ten University Student Nomination Award
2013 National Scholarship Principal Scholarship/Top Ten University Student Nomination Award
2020 First Prize for Poster Presentation of the 5th National Conference on Developmental Biology
2021 Advanced Innovation Fellow, Beijing Advanced Innovation Center for Structural Biology

Resume

2010-2014Marine College, Shandong University BS.

2014-2020School of medicine, Tsinghua University Ph.D.

2020-PresentSchool of medicine, Tsinghua University Postdoc.

Main Reaearch Fields

Cellular metabolic state and epigenetic landscape are mutually regulated. I will combine structural and functional methods to investigate the recognition of epigenetic modifications and the regulation mechanism of gene expression.

Selected Publications

1. Ren, X., Zhou, Y., Xue, Z., Hao, N., Li, Y., Guo, X., Wang, D., Shi, X. and Li, H. (2021) Histone benzoylation serves as an epigenetic mark for DPF and YEATS family proteins. Nucleic Acids Res, 49, 114-126.

2. Liu, G.*, Zheng, X.*, Guan, H.*, Cao, Y., Qu, H., Kang, J., Ren, X., Lei, J., Dong, M.Q., Li, X. et al. (2019) Architecture of Saccharomyces cerevisiae SAGA complex. Cell Discov, 5, 25.

3. Zhang, W.*, Zhang, X.*, Xue, Z.*, Li, Y.*, Ma, Q., Ren, X., Zhang, J., Yang, S., Yang, L., Wu, M. et al. (2019) Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants. Dev Cell, 48, 406-419 e405.