Contact information

Runyu Guo Ph.D.

2016 National Scholarship
2016 10 Major Advances in Life Science by CAST
2017 Future Scholarship
2017 National Scholarship
2017 Outstanding Ph.D. candidate by ICSB
2018 National Scholarship


2011-2015Tsinghua University, Beijing B.S.

2015-2019Tsinghua University, Beijing Ph.D.

2019-presentTsinghua University, Beijing Postdoc fellow

Main Reaearch Fields

To explain the molecular mechanism of cell respiration by analyzing the three-dimensional structure of respiratory chain complexes

Selected Publications

1.Zong S*, Wu M*, Gu J*, Liu T*, Guo R*, Yang M. Structure of the intact 14-subunit human cytochrome c oxidase. Cell Res. 2018 Oct;28(10):1026-1034.

2.Guo R, Gu J, Zong S, Wu M, Yang M. Structure and mechanism of mitochondrial electron transport chain. Biomed Journal. 2018 Feb; 41(1):9-20.

3.Zong S*, Gu J*, Liu T*, Guo R*, Wu M*, Yang M. UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer. Protein&Cell. 2018 Jun;9(6):586-591.

4.Guo R*, Zong S*, Wu M*, Gu J*, Yang M. Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell. 2017 Sep 7;170(6):1247-1257.e12.

5.Wu M*, Gu J*, Guo R*, Huang Y, Yang M. Structure of Mammalian Respiratory Supercomplex I1III2IV1. Cell. 2016 Dec 1;167(6):1598-1609.e10.

6.Guo R*, Gu J*, Wu M*, Yang M. Amazing structure of respirasome: unveiling the secrets of cell respiration. Protein&Cell. 2016 Dec;7(12):854-865.

7.Gu J*, Wu M*, Guo R*, Yan K, Lei J, Gao N, Yang M. The architecture of the mammalian respirasome. Nature. 2016 Sep 29;537(7622):639-43.